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Others tolerate the drug but, once meaningful weight reduction is achieved, do not wish to stay on the medication for life
Scientific References GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists: strengthened warnings on acute pancreatitis, including necrotising and fatal cases
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The goal of weight loss treatment is to improve health and well-being, not to cause debilitating side effects
It is tempting to speculate that this apparent loss of benefit in patients with more advanced HF may be the result of increases in HR caused by activation of sinoatrial node (SAN) GLP-1Rs (64, 65), which could be mitigated with an agent such as GLP-1(2836) that retains cardiac and vascular protection of GLP-1, without activating the GLP-1R
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